PARP1 anticorps (N-Term)

N° du produit ABIN220760

L’anticorps Lapin Polyclonal anti-PARP1 a été validé pour WB et IHC. Il convient pour détecter PARP1 dans des échantillons de Humain et Boeuf (Vache).

Aperçu rapide pour PARP1 anticorps (N-Term) (ABIN220760)

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivité: Humain, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PARP1 anticorps

Épitope: N-Term

Specificité: Specifically recognizes the 85kD fragment of cleaved PARP and can be used as marker for detecting apoptotic cells. Species cross-reactivity: Human and bovine. Mouse and rat demonstrate 86 % homology.

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide corresponding to N-terminus of cleavage site (214/215) of human PARP.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: IHC, WB (1:1000)

Usage: Suitable for use in Western Blot, Immunohistochemistry. Western Blot: 1:1000. Positive control: HeLa and Jurkat cells treated with staurosporine.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Dulbecco's PBS (without Mg2+, Ca2+),  pH 7.3, 50 % glycerol, 1 mg/mL BSA (IgG, protease free), 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur PARP1

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Autre désignation: PARP1 / PARP

Sujet: Name/Gene ID: PARP1

Synonyms: PARP1, ADPRT, ADP-ribosyltransferase NAD(+), Adp-ribosyltransferase, ADPRT1, ARTD1, ADPRT 1, Poly(ADP-ribose) synthetase, Poly(ADP-ribosyl)transferase, PARP, Poly [ADP-ribose] polymerase 1, PADPRT-1, PARP-1, Poly (ADP-ribose) polymerase 1, Poly(ADP-ribose) polymerase, Poly[ADP-ribose] synthase 1, PPOL

ID gène: 142

UniProt: P09874

Pathways: Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location